Unruptured intracranial aneurysms (UIAs) are present in approximately 3–5% of the adult population worldwide. Although most aneurysms remain stable and never rupture, aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening event that results in death or persistent neurological deficits for 27% of affected patients within 12 months. Accurately predicting which aneurysms are at greatest risk of rupture remains a significant clinical challenge, as risk varies according to aneurysm location, morphology, and individual patient factors.
Our research uses advanced high-resolution imaging techniques, including 3T and 7T MRI, to identify markers of aneurysm inflammation, growth, and rupture risk. By correlating imaging findings with histopathological analyses, we seek to better understand aneurysm biology, improve risk stratification, and guide earlier intervention for high-risk patients, ultimately reducing the morbidity and mortality associated with aneurysm rupture.
Aneurysms seen in DSA, HR-MRI and Histologically, Published in JNIS 2019.